Chemical structure of cannabidiol. (Photo:Wikimedia Commons)
CBD, or cannabidiol, is quickly changing the debate surrounding the use of marijuana as a medicine.
Most people have heard of a chemical called THC, which is the ingredient in marijuana that gets users high. But recently, attention has shifted to another compound in marijuana called CBD — and for good reason.
Because while doctors can’t seem to look past certain side effects of THC, CBD doesn’t appear to present that problem. On the other hand, evidence of CBD’s medical benefits continues to grow.
Here are five facts that you should know about this unique compound:
1. CBD is a key ingredient in cannabis
CBD and THC levels tend to vary among different plants. Marijuana grown for recreational purposes often contains more THC than CBD.
However, by using selective breeding techniques, cannabis breeders have managed to create varieties with high levels of CBD and next to zero levels of THC. These strains are rare but have become more popular in recent years.
2. CBD is non-psychoactive
Unlike THC, CBD does not cause a high. While this makes CBD a poor choice for recreational users, it gives the chemical a significant advantage as a medicine, since health professionals prefer treatments with minimal side effects.
CBD is non-psychoactive because it does not act on the same pathways as THC. These pathways, called CB1 receptors, are highly concentrated in the brain and are responsible for the mind-altering effects of THC.
A 2011 review published in Current Drug Safety Act concludes that CBD “does not interfere with several psychomotor and psychological functions.” The authors add that several studies suggest that CBD is “well tolerated and safe” even at high doses.
3. CBD has a wide range of medical benefits
Unfortunately, most of this evidence comes from animals, since very few studies on CBD have been carried out in human patients.
But a pharmaceutical version of CBD was recently developed by a drug company based in the UK. The company, GW Pharmaceuticals, is now funding clinical trials on CBD as a treatment for schizophrenia and certain types of epilepsy.
Likewise, a team of researchers at the California Pacific Medical Center, led by Dr. Sean McAllister, has stated that they hope to begin trails on CBD as a breast cancer therapy.
4. CBD reduces the negative effects of THC
CBD seems to offer natural protection against the marijuana high. Numerous studies suggest that CBD acts to reduce the intoxicating effects of THC, such as memory impairment and paranoia.
CBD also appears to counteract the sleep-inducing effects of THC, which may explain why some strains of cannabis are known to increase alertness.
Both CBD and THC have been found to present no risk of lethal overdose However, to reduce potential side effects, medical users may be better off using cannabis with higher levels of CBD.
5. CBD extracted from Marijuana has different legalities than CBD extracted from Industrial Hemp
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